AI/ML Scientist – Protein Foundation Models

Manifold Bio builds AI models for protein therapeutic design, trained on proprietary experimental data generated at unprecedented scale. Our in vivo-centric discovery platform produces millions of experimentally validated protein designs per campaign, creating the datasets that make our models possible and our approach uniquely powerful. We combine high-throughput protein engineering with computational design to create antibody-like drugs and other biologics. Our world-class team of protein engineers, biologists, and computational scientists are working together to aim the platform at therapeutic opportunities where precise targeting is the key to overcoming clinical challenges.

Position

Manifold's AI team is actively training protein foundation models on our proprietary experimental datasets. Our generative antibody design model, mBER, has already demonstrated controllable de novo binder design across multiple million-scale screening campaigns, an...