Associate Director, Cell Therapy Discovery

SUMMARY OF THE ROLE
阿斯利康的细胞治疗研发部门致力于研发新一代细胞疗法，以满足我们临床产品线中尚未满足的重大医疗需求。该候选人应具备细胞治疗项目的科学的专业背景和经验，包括早期研发到工艺开发（PD）及CMC。
Cell Therapy R&D within AstraZeneca is dedicated to discovering, engineering, and developing next generation cellular therapies to address high unmet medical needs across our clinical portfolio. The role holder will provide scientific, technical, and regulatory expertise for cell therapy programs, delivering from discovery through process development (PD) and CMC.
具体职责包括：
1. 负责细胞治疗产品（异体/自体/体内给药/实体瘤CAR T）的设计、优化与临床前开发。
2. 负责装甲策略、逻辑门控设计、基因编辑、成药性研究以及病毒及细胞工艺开发（PD）与CMC。
3. 负责细胞治疗产品的检测方法建立、鉴定与移交。
Specifically, the role holder will be: 
1. Accountable for the design, optimization, and preclinical development of cell therapy products (allo/auto/in vivo/solid tumor CAR-T). 
2. Accountable for armoring strategies, logic gated designs, gene editing, manufacturability and virus and cell manufacture PD/CMC considerations. 
3. Accountable...