Computational Postdoctoral Fellow - Spatial Genomics

About the Role

The Cellular Genomics Programme is seeking a Postdoctoral Fellow to work on integrating mutational and spatial transcriptomic datasets in the Lee‑Six group. The group is focused on studying the earliest stages of childhood cancer by investigating the conditions under which cells with particular cancer‑driving mutations gain a selective advantage over their healthy neighbours. This position will be for a 2 year fixed‑term contract.

About the Team

Henry Lee‑Six is a paediatric pathology registrar. His previous work has been focused on somatic mutations in normal tissues. He is starting a new group in the Cellular Genomics Programme with the aim of understanding the interplay between somatic mutations and development in childhood cancer. A major goal of the group is to investigate the relative contribution of mutation identity, cell state, and microenvironmental context in determining whether a mutant cell progresses to form a tumour. The g...