Human-AI Interaction Designer

About FirstPrinciples

FirstPrinciples is a non-profit research organization building AI infrastructure for discovery in fundamental science. Currently, our work focuses on building systems like Theo, the AI Physicist, which is a domain-specialized system for research in fundamental physics.

We’re a fast-growing, remote-first team of builders, researchers, engineers, and thinkers working across Canada, the US, the UK, and expanding globally. What brings us together is a shared curiosity about how the universe works, and a belief that we can build systems that help us explore it more effectively.

We spend our time working on questions that don’t have clear answers, like how to design AI that can reason through scientific problems, and how the scientific process as a whole might evolve. This is work that sits somewhere between creativity and rigorous thinking, and often requires comfort with ambiguity and iteration. If you’re someone who enjoys tackling big...