PhD Position - C++ Software Engineering of a 3D Cell-Based Tissue Simulation Framework

PhD Position - C++ Software Engineering of a 3D Cell-Based Tissue Simulation Framework

ETH Zürich is a world‑leading university dedicated to advancing science and technology.

Project background

We are seeking a highly motivated PhD student to contribute to the further development of SimuCell3D , a high‑performance C++ framework for simulating 3D tissues of thousands deformable cells—including extracellular matrix and cavities—within a single day (Runser et al., 2024, Nat Comput Sci 4, 299–309; Tweetorial). This platform allows investigation of tissue mechanics, cell polarization, and morphogenetic processes at unprecedented scale.

Your role will include:

• Extending SimuCell3D with advanced numerical solvers for reaction‑diffusion systems
• Enhancing the biophysical capabilities of the C++ framework
• Applying the framework to morphogenetic questions using real imaging data
• Running large‑sc...