Postdoctoral Position in Mechanotyping of Complex Cellular Systems

Postdoctoral Position in Mechanotyping of Complex Cellular Systems

Project background

Cells are mechanically heterogeneous systems composed of proteins, membranes, and compartments with distinct physical properties. In parallel, they continuously sense and respond to diverse mechanical cues from their environment, including adhesion, stiffness, tension, shear, pressure, and confinement. These cues are integrated across wide spatial and temporal scales, from nanometers to tissues, to regulate collective cellular behavior. Mechanobiology seeks to understand how cells, tissues, and organoids perceive, process, and remodel mechanical signals, and how these processes govern fundamental biological functions such as homeostasis, growth, differentiation, migration, development, and apoptosis. Despite major advances, a multiscale understanding of how mechanical information is generated and integrated in complex multicellular systems remains limited. Pro...