Preclinical Programme Leader, Cardiovascular & Metabolic Diseases

The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore's national platform dedicated to advancing RNA‑based medicines and revolutionising drug and vaccine development. NATi's mission is to establish Singapore as a globally recognised hub of excellence in nucleic acid therapeutics research, clinical translation, and commercialisation.

We are seeking a scientific Preclinical Programme Leader, Cardiovascular & Metabolic Diseases, to drive discovery toward clinical development of oligonucleotide (siRNA / ASO) programmes targeting MASH, obesity, and cardiometabolic diseases. The role owns programmes from target validation to selection of a Preclinical Candidate ready for IND‑enabling studies, combining hands‑on laboratory experience and strategic programme management.

• Own end‑to‑end scientific and project strategy for one or more siRNA / ASO discovery programmes from t...