Scientist, Computational Medicinal Chemistry

Monte Rosa Therapeutics
Full-time Basel, Basel-Stadt Other-General
Posted:
February 23, 2026
Location:
Basel, Basel-Stadt, Switzerland

Job Description

Overview

We are seeking a highly motivated, creative Computational Medicinal Chemist to support drug discovery programs. The successful candidate will operate at the interface of computational chemistry and medicinal chemistry, serving as an embedded, project-facing contributor within lead identification and lead optimisation (LI/LO) teams. The position will also involve contributions to earlier drug discovery phases and the development of computational tools with direct application in medicinal chemistry.

This role is strongly project-driven: you will apply computational approaches to directly inform compound design, optimisation, and decision-making, working closely with multidisciplinary teams in chemistry, biology, and data science. The position offers the opportunity to make a tangible impact on the design and optimisation of novel chemical matter, leveraging the company’s core expertise in degrader discovery.

Responsibilities

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Job Overview

Job Type: Full-time
Location: Basel, Switzerland
Posted: February 23, 2026
Deadline: April 04, 2026