Scientist, Nucleic Acid Therapeutics (GIS)

A*STAR
Full-Time Singapore, Singapore Life Scientists
Posted:
March 03, 2026
Location:
Singapore, Singapore, Singapore

Job Description

The Yu Lab at the Genome Institute of Singapore (GIS), A*STAR is seeking highly motivated Scientists to join our Chemical Biology team and drive innovative discovery in nucleic acid therapeutics, with a focus on antisense oligonucleotides (ASOs) and RNA-targeted precision medicine.


Our lab specializes in engineering molecular tools to modulate cellular nucleic acids for therapeutic benefit. This position centers on advancing ASO platforms and complementary RNA-targeting strategies to address diseases rooted in genomic dysregulation and currently undruggable pathways. This project aims to develop next-generation ASOs for gene-selective modulation, integrating chemical biology, RNA biology, and functional genomics.


Contract Length: 13-month contract for the first instance.

Key Responsibilities


Nucleic Acid Therapeutics Development

  • Lead the design, optimization, and evaluation of RNA-targeting modalities, w...
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    Job Overview

    Job Type: Full-Time
    Location: Singapore, Singapore
    Posted: March 03, 2026
    Deadline: April 12, 2026