Senior Scientist, Respiratory Discovery

Merck
Full-time South San Francisco, CA other-general
Posted:
June 13, 2026
Location:
South San Francisco, CA, United States

Job Description

**Job Description**

The Senior Scientist will join the Respiratory Biology Discovery group and contribute to target identification, translational biology, and mechanism‑of‑action studies supporting early discovery programs in chronic lung diseases, including COPD, bronchiectasis, asthma, pulmonary fibrosis, and inflammatory airway diseases.

The successful candidate will apply human‑relevant in vitro and ex vivo experimental systems, with an emphasis on primary airway epithelial biology, mesenchymal and immune‑epithelial interactions, disease‑relevant functional assays, and translational biomarkers. This individual will generate high‑quality mechanistic datasets, support biomarker discovery and translational efforts, and collaborate closely within multidisciplinary discovery and translational teams.

**Key Responsibilities:**

+ Design, execute, and interpret in vitro and ex vivo studies to support respiratory target validation and translational biology...

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Job Overview

Job Type: Full-time
Location: South San Francisco, United States
Posted: June 13, 2026
Deadline: June 18, 2026